C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/705 (2006.01) C12N 1/11 (2006.01) C12N 15/63 (2006.01)
Patent
CA 2047683
The present invention discloses a new neuronal nicotinic acetylcholine receptor subunit, .beta.4. The new subunit can form functional combinations with other neuronal nicotinic acetylcholine receptor subunits, including, but not limited to, alpha2; alp-Ha3, alpha4 and beta2. A cDNA clone containing the DNA sequences that encode the novel receptor subunit of the invention has been deposited with the American Type Culture Collection for patent purposes.
L'invention concerne une nouvelle sous-unité beta4 de récepteurs d'acétylcholine nicotinique neuronaux. La nouvelle sous-unité peut former des combinaisons fonctionnelles avec d'autres sous-unités de récepteurs d'acétylcholine nicotinique neuronaux comprenant entre autres alpha2, alpha3, alpha4 et bêta2. Un clone d'ADNc contenant les séquences d'ADN codant la nouvelle sous-unité de récepteurs de l'invention a été déposé auprès de l'American Type Culture Collection pour être breveté.
Deneris Evan S.
Duvoisin Robert M.
Heinemann Stephen F.
Patrick James W.
Macrae & Co.
The Salk Institute For Biological Studies
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