Neuronal nicotinic acetylcholine receptor compositions and...

C - Chemistry – Metallurgy – 12 – N

Patent

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530/13, 150/19,

C12N 15/12 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) G01N 33/566 (2006.01) G01N 33/567 (2006.01)

Patent

CA 1341554

The present invention relates to a family of neuronal nicotinic acetylcholine receptors comprised of neuronal agonist and non-agonist binding subunits, and DNA sequences encoding such subunits. These novel neuronal nicotinic acetylcholine receptor subunits include the agonist binding subunits alpha2, alpha3, alpha4, and alpha5, plus non-agonist binding subunits beta2, beta3 and beta4. Representative cDNA clones that contain the DNA sequences of the invention have been deposited with the American Type Culture Collection for patent purposes.

594211

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