C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/06 (2006.01) C07K 14/47 (2006.01) C12N 5/08 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2295305
The invention relates to a method for isolating a neuroblastic cell from a population of cells comprising the steps of: (a) detecting the expression of the Sox1 gene in the cells; and (b) sorting the cells to isolate those cells expressint the Sox1 gene, as well as to a method for causing a cell to become committed to the neural pathway comprising administering SOX1 thereto.
L'invention concerne une méthode d'isolement d'un neuroblaste à partir d'une population de cellules, la méthode consistant: (a) à détecter l'expression du gène Sox1 dans les cellules; et (b) à trier les cellules pour isoler les cellules isolant le gène Sox1; l'invention concerne également une méthode destinée à provoquer l'engagement d'une cellule dans le trajet neuronal, la méthode consistant à lui administrer SOX1.
Episkopou Vasso
Lovell-Badge Robin
Pevny Laryssa H.
Smith Austin
Medical Research Council
Sim & Mcburney
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