Neuropeptide-2 receptor (y-2r) agonists and uses thereof

Details Neuropeptide-2 receptor (y-2r) agonists and uses thereof Neuropeptide-2 receptor (y-2r) agonists and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 14/575 (2006.01)

Patent

CA 2734385

The invention relates to neuropeptide-2 receptor agonists of the formula (I): Y-R1-R2-X-R3-R4-R5-R6-R7-R8-R9-R10- R11-R12-R13-R14-NH2, as well as pharmaceutically acceptable salts, derivatives and fragments thereof, wherein the substituents are as those disclosed in the specification. These compounds and the pharmaceutical compositions containing them are useful for the treatment of diseases such as, for example, obesity and diabetes.

L'invention porte sur des agonistes du récepteur du neuropeptide-2 représentés par la formule (I) : Y-R1-R2-X-R3-R4-R5-R6-R7-R8-R9-R10-R11-R12-R13-R14-NH2, ainsi que sur des sels, dérivés et fragments pharmaceutiquement acceptables de ceux-ci, dans laquelle formule les substituants sont tels qu'exposés dans la description. Ces composés et les compositions pharmaceutiques les contenant sont utiles pour le traitement de maladies telles que, par exemple, l'obésité et le diabète.

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