C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/705 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01) G01N 33/566 (2006.01) G01N 33/74 (2006.01)
Patent
CA 2392309
This invention relates to the identification of an orphan G-protein coupled receptor EBI2 (and variants thereof) as a receptor of neuropeptides of the CRF family, and the use of such peptides, e.g. urotensin I or sauvagine (and analogues or mimetics of either one) as modulators for EBI2. It also relates to screening methods to identify agonists and antagonists for this neuropeptide receptor.
Fidock Mark David
Robas Nicola Melanie
Pfizer Inc.
Smart & Biggar
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