Neuropeptide y agonists

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/47 (2006.01) A61K 38/10 (2006.01) A61K 38/17 (2006.01) C07K 7/08 (2006.01) C07K 14/575 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2257424

The present invention relates to Neuropeptide Y receptor ligands derived from alanine substitutions of the NPY24-36 amino acid sequence. The ligands may be used, for example, in the treatment or rhinitis, respiratory diseases and vasoconstriction predisposing to acute renal failure.

La présente invention concerne des ligands des récepteurs du neuropeptide Y, lesquels ligands dérivent de substitutions alanine de la séquence d'acide aminé NPY24-26. Ces ligands conviennent notamment au traitement des rhinites, d'affections respiratoires et d'affections à vasoconstriction prédisposant à l'insuffisance rénale aiguë.

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