Neuropeptide-y ligands

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 409/12 (2006.01) A61K 31/17 (2006.01) A61K 31/34 (2006.01) A61K 31/35 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) A61K 31/4406 (2006.01) A61K 31/445 (2006.01) A61K 31/47 (2006.01) A61K 31/505 (2006.01) C07C 275/26 (2006.01) C07C 275/28 (2006.01) C07C 279/24 (2006.01) C07D 211/08 (2006.01) C07D 213/40 (2006.01) C07D 213/56 (2006.01) C07D 213/58 (2006.01) C07D 215/12 (2006.01) C07D 233/61 (2006.01) C07D 235/14 (2006.01) C07D 239/32 (2006.01) C07D 265/30 (2006.01) C07D 307/14 (2006.01) C07D 307/2

Patent

CA 2268051

There are disclosed novel neuropeptide Y ligands having general formula (I) wherein the symbols W, A, D, R1, R2, R3, R4 are further defined in the description. Compounds of formula (I) are agonists and antagonists of neuropeptide Y, and are therefore useful as regulators of neuropeptide Y activity and in treating disorders related thereto.

L'invention concerne de nouveaux ligands du neuropeptide Y de la formule générale (I), dont les symboles W, A, D, R?1¿, R?2¿, R?3¿, R?4¿ sont définis dans la description. Les composés de ladite formule (I) constitue des agonistes et des antagonistes du neuropeptide Y et peuvent donc être utilisés comme régulateurs de l'activité du neuropeptide Y et pour le traitement de troubles liés à cette activité.

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