Neuroprotective 2-pyridinamine compositions and related methods

A - Human Necessities – 61 – K

Patent

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A61K 31/44 (2006.01) A61K 31/443 (2006.01) A61K 31/4433 (2006.01) A61K 31/4439 (2006.01) A61K 31/444 (2006.01) A61K 31/506 (2006.01) A61K 31/5355 (2006.01) A61K 31/5377 (2006.01) A61P 9/10 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2418912

This invention provides neuroprotective pharmaceutical compositions comprising 2-pyridinamines. This invention also provides methods of using these compositions to prevent ischemic cell death, particularly neuronal cell death, and reduce the likelihood of neuronal cell death in a subject due to a traumatic event. Finally, this invention provides an apparatus for administering to a subject the instant pharmaceutical compositions.

L'invention concerne des compositions pharmaceutiques neuroprotectrices comprenant des 2-pyridinamines. L'invention concerne également des méthodes d'utilisation de ces composant pour la prévention de la mort cellulaire causée par ischémie, en particulier la mort cellulaire neuronale, et réduire le risque d'une mort cellulaire neuronale chez un sujet à la suite d'un traumatisme. Enfin cette invention concerne une dispositif permettant l'administration de ces compositions pharmaceutiques à un sujet.

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