Neuroprotective 3-piperidino-4-hydrosychroman derivatives

Details Neuroprotective 3-piperidino-4-hydrosychroman derivatives Neuroprotective 3-piperidino-4-hydrosychroman derivatives

C - Chemistry, Metallurgy

07

D

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C07D 405/04 (2006.01) A61K 31/435 (2006.01) C07D 211/14 (2006.01) C07D 211/18 (2006.01) C07D 211/48 (2006.01) C07D 211/52 (2006.01) C07D 451/02 (2006.01) C07D 451/06 (2006.01) C07D 471/08 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2035653

3-Piperidino-1-chromanol derivatives and analogs having the formula (see formula I) wherein A and B are taken together and are -CH2CH2- or A and B are taken separately and are each H; X is CH2 or O; X1 is H or OH; Z is H, F, Cl, Br or OH; Z1 is H, F, Cl, Br or (C1-C3)alkyl; n is 0 or 1; and m is 0 or an integer from 1 to 6; pharmaceutical compositions thereof; methods of treating CNS disorders therewith; and intermediates useful in the preparation of said compounds.

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