Neuroprotective composition and uses thereof

Details Neuroprotective composition and uses thereof Neuroprotective composition and uses thereof

A - Human Necessities

61

K

A61K 31/19 (2006.01) A61K 31/23 (2006.01) A61K 31/355 (2006.01) A61K 45/06 (2006.01) A61P 9/00 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2373039

A neuroprotective composition for protecting neuronal cells against oxidative stress and methods for using and preparing the same. More particularly, the neuroprotective composition of the invention comprises a mixture of pyruvate, antioxidant, and lipid(s) such as fatty acids. The neuroprotective composition could be used for the treatment of brain trauma, brain or cerebrovascular ischemia, neurodegenerative diseases, poisoning of neuronal cells, the diminution of drugs side effects and for preservation of neuronal grafts.

L'invention concerne une composition neuroprotectrice, permettant de protéger des cellules neuronales contre les contraintes oxydatives, et des techniques de préparation et d'utilisation de cette composition. La composition neuroprotectrice comprend, en particulier, un mélange de pyruvate, d'antioxydant, et de lipide(s) tels que les acides gras. Elle peut être utilisée pour traiter un traumatisme cérébral, une ischémie cérébrale ou cérébrovasculaire, des maladies neurodégénératives, l'empoisonnement des cellules neuronales, la diminution des effets secondaires des médicaments, et pour préserver les greffes neuronales.

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