Neuroprotective peptides

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/00 (2006.01) C07K 2/00 (2006.01) C07K 5/00 (2006.01) C07K 7/00 (2006.01) C07K 14/505 (2006.01)

Patent

CA 2410453

Methods of treating diseases of the nervous system by administration of compositions having the neurological therapeutic activity of human erythropoietin are disclosed. These compositions include therapeutic agents such as peptides, peptide dimers, polypeptides, and proteins that have the full range of biological activity of human erythropoietin or only certain biological activities of erythropoietin. Improved therapeutic regimens where the erythropoietin is administered at concentrations below those required to stimulate hematopoiesis are also provided.

L'invention concerne des procédés destinés au traitement de maladies du système nerveux par administration de compositions possédant l'activité thérapeutique et neurologique de l'érythropoïétine humaine. Ces compositions contiennent des agents thérapeutiques, tels que des peptides, des dimères peptidiques, des polypeptides, et des protéines possédant la gamme complète des activités biologiques de l'érythropoïétine humaine ou seulement certaines d'entre elles. L'invention porte également sur des posologies thérapeutiques améliorées dans lesquelles l'érythropoïétine est administrée dans des concentrations inférieures à celles requises dans la stimulation de l'hématopoïèse.

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