Neurotensin active 2,3-diaryl-pyrazolidine derivatives

Details Neurotensin active 2,3-diaryl-pyrazolidine derivatives Neurotensin active 2,3-diaryl-pyrazolidine derivatives

C - Chemistry, Metallurgy

07

D

C07D 231/04 (2006.01) A61K 31/415 (2006.01) A61P 25/00 (2006.01) C07D 401/04 (2006.01)

Patent

CA 2462694

The invention relates to a group of novel 2,3 diaryl-pyparazolidine derivatives having formula (1). The symbols used in formula (1) have the meanings given in the specification. The compounds have inhibiting activity on enzymes which degrade the neuropeptide neurotensin and can be used for the treatment of affections and diseases caused by disturbances of the neurotensin mediated transmission.

L'invention concerne un groupe de nouveaux dérivés de 2,3-diaryl-pyrazolidine de la formule (1). Les symboles utilisés dans la formule (1) ont la signification donnée dans le descriptif. Les composés présentent une activité inhibitrice sur les enzymes qui dégradent le neuropeptide neurotensine et peuvent être utilisés dans le traitement d'affections et de maladies causées par des troubles de la transmission induite par la neurotensine.

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