Neurotrophic peptides

Details Neurotrophic peptides Neurotrophic peptides

C - Chemistry, Metallurgy

07

K

530/7.06, 167/10

C07K 7/06 (2006.01) A61K 38/08 (2006.01) C07K 14/475 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2013300

ABSTRACT OF THE DISCLOSURE A novel neurotrophic peptide which exhibits biological activity enhancing acetylcholine synthesis in cholinergic neurons is isolated and purified from a water soluble fraction of hippocampal tissue in mammals. A derivative of the peptide having the same biological activity may be chemically synthesized using a conven- tional solid or liquid phase method. The peptide and derivative thereof are useful for the treatment of neurological degenerative disorders and dementia.

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