A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/70 (2006.01) A61K 31/7034 (2006.01) A61P 21/00 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01) C07H 15/207 (2006.01)
Patent
CA 2318584
Inositolphosphoglycans (IPGs) or inositol-containing IPG analogues can be used to specifically cause neuron proliferation or neuron differentiation, and in particular neurite outgrowth. P-type IPGs or chiro-inositol containing analogues cause neurite outgrowth and A-type IPGs or myo-inositol containing analogues cause neuron proliferation. Compositions comprising these agents and their medical uses are also disclosed.
La présente invention concerne des inositolphosphoglycannes (IPG) ou IPG contenant de l'inositol utilisables pour provoquer de manière spécifique la prolifération ou la différenciation des neurones, et notamment dans l'excroissance des axones et de dendrites. Les IPG de type P ou des analogues contenant du chiro-inositol provoquent l'excroissance des axones et de dendrites et les IPG de type A ou les analogues contenant du myo-inositol provoquent la prolifération des neurones. L'invention concerne également les compositions comprenant lesdits agents et leur utilisation à des fins médicales.
Alvarez Yolanda Leon
Caro Hugo Norberto
Martin-Lomas Manuel
Nieto Isabel Varela
Rademacher Thomas William
Bereskin & Parr
Rademacher Group Limited
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