Neurotrophic tacrolimus analogs

Details Neurotrophic tacrolimus analogs Neurotrophic tacrolimus analogs

A - Human Necessities

61

K

A61K 31/44 (2006.01)

Patent

CA 2433384

Tacrolimus derivatives having high levels of neurotrophic activity and low levels of immunosuppresive activity. These compounds are useful as neurotrophic agents, particularly, for preventing or treating neuronal injury/dysfunction.

L'invention concerne des dérivés de tacrolimus présentant des niveaux élevés d'activité neurotrophique et de faibles niveaux d'activité immunosuppressive. Ces composés constituent des agents neurotrophiques très utiles, en particulier dans la prévention ou le traitement d'une lésion/dysfonction neuronale.

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