Neurturin receptor

Details Neurturin receptor Neurturin receptor

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 1/22 (2006.01) C07K 14/71 (2006.01) C07K 16/28 (2006.01) C07K 16/46 (2006.01) C07K 19/00 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2281620

NTNR.alpha., NTNR.alpha. extracellular domain (ECD), NTNR.alpha. variants, chimeric NTNR.alpha. (e.g., NTNR.alpha. immunoadhesion), and antibodies which bind thereto (including agonist and neutralizing antibodies) are disclosed. Various uses for these molecules are described, including methods to modulate cell activity and survival by response to NTNR.alpha.-ligands, for example NTN, by providing NTNR.alpha. to the cell.

L'invention concerne le récepteur de la neurturine .alpha. (NTNR.alpha.), le domaine extracellulaire (ECD) du NTNR.alpha., des variants du NTNR.alpha., un NTNR.alpha. chimère (tel qu'une immuno-adhésine du NTNR.alpha.) et des anticorps qui se fixent sur le NTNR.alpha. (notamment des anticorps agonistes et neutralisants). Elle concerne également diverses utilisations de ces molécules, notamment des méthodes permettant de moduler l'activité et la survie des cellules par une réponse aux ligands du NTNR.alpha., par exemple la neurturine, en fournissant à la cellule des NTNR.alpha..

Affiliated with

Also associated with

Rating

Neurturin receptor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Neurturin receptor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Neurturin receptor will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1832507