Neutralization of bacterial spores

Details Neutralization of bacterial spores Neutralization of bacterial spores

A - Human Necessities

61

K

A61K 38/16 (2006.01) A61K 9/00 (2006.01) A61K 31/43 (2006.01) A61K 31/496 (2006.01) A61K 31/65 (2006.01) A61K 31/7048 (2006.01) A61K 31/7052 (2006.01) A61P 31/04 (2006.01) A61M 15/00 (2006.01)

Patent

CA 2641854

The present invention relates to the field of bacteriology. In particular, the present invention provides compositions (e.g., a lantibiotic-based spore decontaminant (e.g., comprising nisin)) and methods of neutralizing (e.g., killing or inhibiting growth or inhibiting germination of) bacteria (e.g., cells and spores). For example, the present invention provides nisin-based compounds (e.g., for bacterial spore decontamination) and methods of using the same in research, therapeutic and drug screening applications.

L'invention se rapporte au domaine de la bactériologie. L'invention concerne en particulier des compositions (par exemple, un décontaminant pour spores à base de lantibiotique (par exemple, comprenant de la nisine) et des méthodes de neutralisation (par exemple, visant à éliminer ou à inhiber la croissance ou à inhiber la germination) de bactéries (par exemple, cellules et spores). L'invention propose par exemple des composés à base de nisine (par exemple, pour la décontamination de spores bactériennes) et des méthodes d'utilisation de ceux-ci dans la recherche, à des fins thérapeutiques et dans des applications de criblage de médicaments.

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