C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/00 (2006.01) A61P 31/16 (2006.01)
Patent
CA 2731686
The invention relates to antibodies, and antigen binding fragments thereof, that bind to hemagglutinin and neutral-ize a group 1 subtype and a group 2 subtype of influenza A virus The invention also relates to nucleic acids that encode, immor-talized B cells and cultured single plasma cells that produce, and to epitopes that bind to such antibodies and antibody fragments In addition, the invention relates to the use of the antibodies, antibody fragments, and epitopes in screening methods as well as in the diagnosis, treatment and prevention of influenza A virus infection
L'invention concerne des anticorps, et des fragments de liaison antigénique de ceux-ci, qui se lient à lhémagglutinine et neutralisent un sous-type du groupe 1 et un sous-type du groupe 2 du virus influenza A. La description concerne également des acides nucléiques qui codent pour, des cellules B immortalisées et des cellules plasmatiques uniques cultivées qui produisent, et des épitopes qui se lient à, ces anticorps et fragments danticorps. Linvention concerne en outre l'utilisation des anticorps, des fragments d'anticorps, et des épitopes dans des procédés de dépistage ainsi que dans le diagnostic, le traitement et la prévention dune infection par le virus influenza A.
Institute For Research In Biomedicine
Mbm Intellectual Property Law Llp
LandOfFree
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