C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/495 (2006.01) A61K 38/18 (2006.01) C12N 15/18 (2006.01) C12N 15/62 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2551877
The invention provides new, specific antigenic peptides from the protein GDF8. The invention also provides fusion proteins comprising the new peptides, immunogens and vaccines based on the new peptides and/or fusion proteins, antibodies that specifically bind to the new peptides of GDF8, and methods of treating animals in order to modulate the activity of GDF8, employing vaccines or antibodies according to the invention.
L'invention concerne de nouveaux peptides antigéniques spécifiques issus de la protéine GDF8. Elle concerne également des protéines hybrides contenant ces nouveaux peptides, des immunogènes et des vaccins à base de ces nouveaux peptides et/ou de ces protéines hybrides, des anticorps se liant spécifiquement à ces nouveaux peptides de la GDF8, et des méthodes de traitement des animaux en vue de moduler l'activité de la GDF8, à l'aide des vaccins ou des anticorps selon la présente invention.
Cochran Mark D.
Junker David E.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Schering-Plough Ltd.
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