Neutralizing human monoclonal antibodies specific for the v3...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/10 (2006.01) A61K 39/21 (2006.01) A61K 39/42 (2006.01) A61K 47/48 (2006.01) C07K 14/16 (2006.01) C07K 16/10 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2094713

2094713 9207878 PCTABS00013 Anti-HIV-1 antibodies directed against the V3 loop and the CD-4 binding site of gp120 synergistically neutralize. Certain antibodies neutralize the IIIB, MN, SF-2 and RF strains.

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