Neutralizing molecules to viral antigens

Details Neutralizing molecules to viral antigens Neutralizing molecules to viral antigens

C - Chemistry, Metallurgy

07

K

C07K 16/10 (2006.01) A61K 39/145 (2006.01)

Patent

CA 2719201

The present invention concerns methods and means for identifying, producing, and engineering neutralizing molecules against influenza A viruses, and to the neutralizing molecules produced. In particular, the invention concerns neutralizing molecules against various influenza A virus subtypes, including neutralizing antibodies against H5 and/or H3 and/or H1, such as, for example all of H1, H3, and H5 subtypes, and methods and means for making such molecules.

La présente invention concerne des procédés et des moyens d'identification, de production et de conception de molécules neutralisant les virus de la grippe A et les molécules neutralisantes ainsi produites. En particulier, l'invention concerne des molécules neutralisant les différents sous-types du virus de la grippe A, y compris les anticorps neutralisant les H5 et/ou H3 et/ou H1 tels que, par exemple, tous les sous-types H1, H3 et H5, ainsi que les procédés et moyens de fabrication de telles molécules.

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