New 2,9-dioxatricyclo[4,3,1,0 su3,7 xx] decane derivatives,...

Details New 2,9-dioxatricyclo[4,3,1,0 su3,7 xx] decane derivatives,... New 2,9-dioxatricyclo[4,3,1,0 su3,7 xx] decane derivatives,...

C - Chemistry, Metallurgy

07

D

260/351, 260/380

C07D 319/08 (2006.01) C07D 493/08 (2006.01)

Patent

CA 1098528

ABSTRACT OF THE DISCLOSURE New 2,9-dioxatricyclo[4,3,1,O3,7) decane deriva- tives are disclosed which are substituted by an amino methyl group in the C3 position, and which exhibit sedative , especially sleep improving properties, and which have the formula Image (I) wherein R1 represents an amino group one of R2 and R3 is hydrogen and the other represents hydroxy acyloxy or carbamyloxy or R2 and R3 jointly represent oxygen one of R4 and R5 is hydrogen and the other represents alkyl- oxy or aralkyloxy y and y' each represent hydrogen or jointly form a bond and their pharmacologically acceptable salts, as well as pharmaceutical formulations thereof.

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