New [(3-alkoxy-phenoxy)-ethyl]-dialkylamine derivatives and...

C - Chemistry – Metallurgy – 07 – C

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C07C 217/20 (2006.01) A61K 31/135 (2006.01)

Patent

CA 2233489

There is provided compounds of formula (I), wherein R1 represents C3-5 alkyl; and R2 and R3 independently represent C1-3 alkyl; provided that when R2 and R3 both represent ethyl, then R1 does not represent n-butyl, i-butyl or n-pentyl; or a pharmaceutically acceptable salt thereof, which are useful as anaesthetics, in particular local anaesthetics and especially topically applied local anaesthetics.

La présente invention concerne des composés de formule (I), dans laquelle R<1> représente alkyle C3-5 et R<2> et R<3> représentent de manière indépendante alkyle C1-3, à condition que, quand R<2> et R<3> représentent éthyle tous les deux, R<1> ne représente pas n-butyle, i-butyle ou n-pentyle. L'invention concerne aussi les sels de ces composés acceptables en pharmacie. Ces substances sont utiles comme anesthésiques, en particulier comme anesthésiques locaux, spécialement pour l'application topique.

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