New 3-/substituted tetrazolyl/-4-oxo-4h-pyrido-/1,2-a/-...

Details New 3-/substituted tetrazolyl/-4-oxo-4h-pyrido-/1,2-a/-... New 3-/substituted tetrazolyl/-4-oxo-4h-pyrido-/1,2-a/-...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/505 (2006.01)

Patent

CA 2114145

2114145 9304065 PCTABS00020 The present invention relates to therapeutically useful 4-oxo-4H-pyrido[1,2-a]-pyrimidines of general formula (I) and/or formula (II), wherein R means C1-6alkyl, C3-6alkenyl, C3-6alkynyl, C3-7cycloalkyl, C1-4alkoxycarbonyl group or C7-8aralkyl group, optionally substituted by one or more halogen atom(s), or by nitro-group, R1 stands for hydrogen atom or a C1-4alkyl group, and salts thereof, further to a process for their preparation, and pharmaceutical compositions containing them. These new compounds may be therapeutically useful first of all as gastroprotectives in the treatment and prevention of ulcer.

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