C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/06 (2006.01) A61K 31/395 (2006.01) A61K 38/05 (2006.01) C07D 213/74 (2006.01) C07D 401/12 (2006.01) C07D 405/14 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2157215
Compounds of formula I (I), Image in which R1 denotes an aryl, a heteroaryl or a cycloalkyl group which can be substituted if desired, AS denotes an amino acid n denotes the numbers 0 or 1, R2 and R3 are the same or different and denote hydrogen atoms, alkyl, carboxyalkyl or alkoxycarbonyl- alkyl groups, or R2 and R3 together with the nitrogen atom to which they are bound, form a heterocyclyl ring which, if desired, can in addition contain a second heteroatom and can be substituted by alkyl, carboxy or alkoxycarbonyl groups, R4 and R5 are the same or different and denote hydrogen atoms or alkyl groups, m denotes the numbers 0, 1 or 2, R6, R7, R8 and R9 are the same or different and denote hydrogen atoms or halogen atoms, as well as hydrates, solvates and their physiologically tolerated salts thereof. The invention also concerns optically active forms, racemates and diastereomer mixtures of these compounds and processes for their production and pharmaceutical agents which contain these compounds in particular for the production of pharmaceutical agents for the treatment of thromboembolic diseases.
Leinert Herbert
Poll Thomas
Stegmeier Karlheinz
von Der Saal Wolfgang
Boehringer Mannheim Gmbh
Swabey Ogilvy Renault
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