New 4-arylpiperidine derivatives for the treatment of pruritus

C - Chemistry – Metallurgy – 07 – D

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C07D 211/34 (2006.01) A61K 31/4465 (2006.01) A61K 31/4523 (2006.01) A61P 1/10 (2006.01) A61P 17/04 (2006.01) C07D 211/14 (2006.01) C07D 211/22 (2006.01) C07D 211/26 (2006.01) C07D 211/32 (2006.01) C07D 401/00 (2006.01)

Patent

CA 2309434

There is provided a compound of formula I, (see above formula) wherein A, D, R1, R2, R3, X and n have meanings given in the description, which are useful in the prophylaxis and in the treatment of diseases mediated by opiate receptors, such as pruritus.

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