New 4-methyl-1, 3-oxazole derivatives, process for their...

C - Chemistry – Metallurgy – 07 – D

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C07D 263/32 (2006.01) A61K 31/42 (2006.01) A61K 31/445 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2111152

ABREGE Composé de formule (I) : Image (I) dans laquelle : R1 représente un groupement 1-adamantyl, dicyclopropylméthyle, cycloalkyle (C3-C6) substitué ou non, bicyclo[2.2.2]oct-1-yl substitué ou non, R2 représente un groupement . Image ou . Image dans lequel : m représente 1, 2 ou 3, X représente un atome d'oxygène, de soufre ou un groupement N-R, R3 ou R4, identiques ou différents, représentent un atome d'hydrogène, un groupement alkyle (C1-C6), trifluorométhyle, ou Image forme un radical cycloalkyle (C3-C6), n représente 0, 1 ou 2, R5 représente un groupement hydroxy, alkoxy (C1-C6), amino substitué ou non ou - O - CH2 - CO - NRR' .

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