New a83543 compounds and process for production thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 1/20 (2006.01) A01N 43/22 (2006.01) A01N 45/02 (2006.01) A01N 63/02 (2006.01) A01P 7/00 (2006.01) A61K 31/7048 (2006.01) A61P 33/14 (2006.01) C07H 17/08 (2006.01) C12P 19/62 (2006.01) A61K 31/71 (1995.01)

Patent

CA 2156194

New A83543 components, including fermentation products A83543K, A835430, A83543P, A83543U, A83543V, A83543W and A83543Y and N-demethyl derivatives, and salts thereof, are useful for the control of insects and mites. The pseudoaglycones of the new A83543 components are useful for the preparation of A83543 components. Methods are provided for making the new A83543 components by culturing of Saccharopolyspora spinosa NRRL 18395, NRRL 18537, NRRL 18538, or NRRL 18539, or NRRL 18743 or NRRL 18719 or NRRL 18823 in suitable culture medium. Insecticidal and ectoparasiticidal compositions containing new A83543 components are also provided.

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