New active marine alkaloids

Details New active marine alkaloids New active marine alkaloids

C - Chemistry, Metallurgy

07

D

C07D 471/18 (2006.01) A61K 31/4995 (2006.01) A61P 35/00 (2006.01) C07D 221/00 (2006.01) C07D 241/00 (2006.01)

Patent

CA 2384656

New antitumour alkaloids of general formula (I) where R1 is hydrogen, alkyl or acyl and R2 is hydrogen or acyl, include jorumycin, where R1 is hydrogen and R2 is acetyl, extracted from the mollusc Jorunna funebris.

L'invention se rapporte à de nouveaux alcaloïdes antitumoraux représentés par la formule (I) dans laquelle R?1¿ est hydrogène, alkyle ou acyle et R?2¿ est hydrogène ou acyle. Ces alcaloïdes comprennent la jorumycine, dans laquelle R?1¿ est hydrogène et R?2¿ est acétyle et qui est extraite du mollusque Jorunna funebris.

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