C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 31/70 (2006.01) A61K 39/106 (2006.01) A61K 39/40 (2006.01) A61K 48/00 (2006.01) C07K 14/205 (2006.01) C07K 16/12 (2006.01) C07K 19/00 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2232730
The invention relates to an adherence gene AlpB from Helicobacter pylori and the polypeptide coded therefrom. This gene was achieved by transposon TnMax9 insertion (mutagenesis) from the chromosome of H-pylori and is characterised by the cloning and sequencing of the downstream AlpA flanked region. These two adherence genes tend to be part of the same operon and to be transcribed by only one promoter.
L'invention concerne un gène d'adhérence AnpB obtenu à partir de Helicobacter pylori et le polypeptide codé par celui-ci. Ce gène a été obtenu par l'insertion du transposon TnMax9 (mutagenèse du chromosome de H-pylori) et se caractérise par le clonage et le séquençage de la région adjacente AlpA située en aval. Ces deux gènes d'adhérence appartiennent probablement au même opéron et sont vraisemblablement transcrits par un seul promoteur.
Blum Andre
Corthesy-Theulaz Irene
Haas Rainer
Meyer Thomas F.
Odenbreit Stefan
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.v.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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