C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 233/29 (2006.01) A61K 31/16 (2006.01) A61K 31/33 (2006.01) A61P 3/00 (2006.01) C07C 235/24 (2006.01) C07C 237/04 (2006.01) C07C 255/60 (2006.01) C07C 275/32 (2006.01) C07D 207/08 (2006.01) C07D 207/09 (2006.01) C07D 207/20 (2006.01) C07D 209/08 (2006.01) C07D 211/46 (2006.01) C07D 211/62 (2006.01) C07D 213/30 (2006.01) C07D 213/56 (2006.01) C07D 295/03 (2006.01) C07D 295/08 (2006.01) C07D 295/092 (2006.01) C07D 295/12 (2006.01) C07D 295/13 (2006.01) C07D 307/42 (2006.01) C07D 333/16 (2006.01)
Patent
CA 2504207
The invention relates to amide compounds of general formula (I), in which the groups and residues A, B, b, W, X, Y, Z, R1, R2 and R3 have the meanings given in claim 1. The invention further relates to medicaments comprising at least one of said amides. Said medicaments are suitable for the treatment of metabolic disorders and/or eating disorders, in particular, obesity, bulimia, anorexia, hyperphagia, and diabetes as a result of the MCH receptor antagonism.
L'invention concerne des composés de type amide de formule générale (I) dans laquelle les groupes et radicaux A, B, b, W, X, Y, Z, R?1¿, R?2¿ et R?3¿ sont tels que définis dans la première revendication. La présente invention se rapporte en outre à des médicaments contenant au moins un amide selon l'invention. Dans la mesure où lesdits composés exercent une action antagoniste sur les récepteurs de l'hormone MCH, l'utilisation des médicaments selon l'invention est appropriée pour traiter des troubles métaboliques et/ou des troubles du comportement alimentaire, en particulier l'obésité, la boulimie, l'anorexie, l'hyperphagie et le diabète.
Arndt Kirsten
Lehmann-Lintz Thorsten
Lenter Martin
Lotz Ralf R. H.
Lustenberger Philipp
Boehringer Ingelheim Pharma Gmbh & Co. Kg
Fetherstonhaugh & Co.
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