New analgesic and nootropic drugs

Details New analgesic and nootropic drugs New analgesic and nootropic drugs

C - Chemistry, Metallurgy

07

D

C07D 451/04 (2006.01) A61K 31/46 (2006.01) C07D 451/10 (2006.01)

Patent

CA 2139739

56 Compounds of general formula : Image where Ar = phenyl or beta-naphtyl, R1 = one or more substituents of the phenyl or beta-naphtyl nucleus, preferably in para position, and selected out of the group consisting of H, CH3, CH2-CH-(CH3)2, O-CH3, Cl, F, Br, CF3, NH2, S-CH3, CN, NO2 R2 = H, CH3, C2H5, CH(CH3)2, R3 = Image Where R4 = H, CH3, C2H5 R5 = H, CH3 X = none O, S, NH, NCH3 Y = O, NH, both in the racemic form and in the isomeric enantiomeric forms, which produce a nootropic effect, i.e. memory enhancement and learning facilitation, as well as an analgesic effect.

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