New anti viral compounds

Details New anti viral compounds New anti viral compounds

C - Chemistry, Metallurgy

07

H

C07H 19/04 (2006.01) A61K 31/70 (2006.01) C07H 19/052 (2006.01) C07H 19/056 (2006.01) C07H 19/06 (2006.01) C07H 19/16 (2006.01)

Patent

CA 2158853

There are provided new compounds having antiviral properties of the formula: B-S-O-Fa, wherein O is oxygen, B-S is a nucleoside analogue in which B represents an optionally substituted heterocyclic ring system, S being a monosaccharide derivative, and Fa is an acyl group of a mono-unsaturated C18 or 20 fatty acid, which fatty acid is esterified with a hydroxyl group of the sugar moiety of the nucleoside analogue or with a hydroxyl group on the non-cyclic group of the nucleosic analogue.

L'invention concerne de nouveaux composés possédant des propriétés antivirales et représentés par la formule B-S-O-Fa, dans laquelle O représente oxygène, B-S représente un analogue de nucléoside où B représente un système de cycle hétérocyclique éventuellement substitué, S étant un dérivé de monosaccharide et Fa représentant un groupe acyle d'un acide gras mono-insaturé C18 ou 20; ledit acide gras est estérifié avec un groupe hydroxyle de la fration sucre de l'analogue de nucléoside, ou avec un groupe hydroxyle du groupe non cyclique de l'analogue de nucléoside.

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