C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 221/24 (2006.01) A61K 31/435 (2006.01) A61P 9/00 (2006.01)
Patent
CA 2394097
There is provided compounds of formula (I), wherein R1, R2, R3 and Ra to Rh have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias, a process for the preparation of compounds of formula (I), and intermediate compounds.
Cette invention concerne des composés représentés par la formule (I) dans laquelle R?1¿, R?2¿, R?3¿ et R?a¿ jusqu'à R?h¿ ont la signification indiquée dans le descriptif. Ces composés conviennent bien pour la prévention et le traitement des arythmies, en particulier auriculaire et ventriculaire. L'invention concerne également un procédé de fabrication des composés de formule (I)ainsi que de composés intermédiaires.
Bjorsne Magnus
Ponten Fritiof
Strandlund Gert
Svensson Peder
Astrazeneca Ab
Fetherstonhaugh & Co.
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