C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 237/20 (2006.01) A61K 31/165 (2006.01) A61K 31/38 (2006.01) A61K 31/435 (2006.01) A61K 31/535 (2006.01) C07C 235/34 (2006.01) C07C 235/36 (2006.01) C07C 237/22 (2006.01) C07D 207/34 (2006.01) C07D 209/02 (2006.01) C07D 213/75 (2006.01) C07D 215/38 (2006.01) C07D 295/185 (2006.01) C07D 333/68 (2006.01) C07F 7/10 (2006.01)
Patent
CA 2061557
ABSTRACT OF DISCLOSURE Novel benzene derivatives are provided of the general formula (I): Image (I) [wherein R1 represents an amino group, a substituted amino group, a protected amino group, or a nitro group; R2 represents an amino group, a substituted amino group, a protected amino group, a hydroxy group, a substituted hydroxy group, or a protected hydroxy group; R3 represents an amino group, a substituted amino, a heterocyclyl group having a ring nitrogen atom as the point of binding, or a substituted heterocyclyl group having a ring nitrogen atom as the point of binding; m is 0 to 2; a is 0 to 6; with the proviso that when m is 0, then n represents an integer from 2 to 6] and salts thereof. Compounds of formula (I) except those wherein R1 is a nitro group have activity in promoting production of nerve growth factor. Compounds of formula (I) wherein R1 is a nitro group are intermediates for compounds of formula (I) wherein R is an amino group.
Matsuda Keiichi
Naruto Shunji
Oda Tomiichiro
Sugano Yuichi
Sugimoto Masahiko
Marks & Clerk
Sankyo Company Limited
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