New benzimidazole, benzoxazole and benzothiazole...

C - Chemistry – Metallurgy – 07 – D

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C07D 403/04 (2006.01) A61K 31/41 (2006.01) A61K 31/415 (2006.01) A61K 31/435 (2006.01) C07D 235/12 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01) C07D 471/04 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2244438

Compound with the formula (I): (see Fig. I) in which: R1 represents a halogen atom or group as defined in the description, Ra, Rb, identical or different, represent a hydrogen atom, an alkyl or hydroxy group, X represents an oxygen or sulfur atom or an NR group, R2 represents an optionally substituted aryl group, R'2 represents a hydrogen atom or optionally substituted aryl group, the isomers thereof and the addition salts thereof with an acid or pharmaceutically acceptable base.

Composé de formule (I): (voir fig. I) dans laquelle: R1 représente un atome d'halogène ou un groupement tel que défini dans la description, Ra, Rb, identiques ou différents, représentent un atome d'hydrogène, un groupement alkyle ou hydroxy, X représente un atome d'oxygène ou de soufre ou un groupement NR, R2 représente un groupement aryle éventuellement substitué, R'2 représente un atome d'hydrogène ou groupement aryle éventuellement substitué, ses isomères ainsi que ses sels d'addition à un acide ou à une base pharmaceutiquement acceptable.

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