New benzimidazolone derivatives displaying affinity at the...

Details New benzimidazolone derivatives displaying affinity at the... New benzimidazolone derivatives displaying affinity at the...

C - Chemistry, Metallurgy

07

D

C07D 235/26 (2006.01) A61K 31/4184 (2006.01) A61K 31/437 (2006.01) A61K 31/438 (2006.01) A61K 31/4439 (2006.01) A61K 31/454 (2006.01) A61K 31/506 (2006.01) A61P 25/22 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 471/04 (2006.01) C07D 471/10 (2006.01)

Patent

CA 2417082

N, N'-Disubtituted benzimidazolone derivatives of general formula (I) wherein R1 is hydrogen, alkyl or cycloaljylalkyl, A is alkenylene and R2 and R3 together with N form sepecified cyclic system are serotonine or dopamine receptor ligands useful in the treatment of anxiety and affective disorders.

Dérivés de benzimidazolone à disubstitution N,N' de formule générale (I) dans laquelle R?1¿ représente hydrogène, alkyle ou cycloakylalkyle, A représente alcénylène et R?2¿ et R?3¿ forment ensemble avec N des systèmes cycliques spécifiés. Lesdits dérivés sont des ligands de récepteurs de sérotonine ou de dopamine, utiles pour traiter l'anxiété et les troubles affectifs.

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