New benzopyran derivatives; process for preparing the same...

C - Chemistry – Metallurgy – 07 – D

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C07D 491/052 (2006.01) A61K 31/40 (2006.01) A61K 31/435 (2006.01) C07D 491/04 (2006.01)

Patent

CA 2153195

Composés de formule (I) Image dans laquelle n représente 1 ou 2, R1 représente un atome d'hydrogène ou un groupement alkyle, benzyle, acétyle, benzoyle, allyle, pyridinecarbonyle, pyridineméthyle, acylaminoalkyle (substitué éventuellement), pyridineaminocarbonyle, phtalimidoalkyle, thiochromanyloxyalkyle ou benzodioxanyloxyalkyle, R2, R3 ou R4, identiques ou différents représentent un atome d'hydrogène, d'halogène ou un groupement alkyle, alkoxy, hydroxy, acétyle, aminocarbonyle, aminométhyle, cyano, nitro, amino, phényle (substitué ou non), furyle, pyridinyle, thiényle ou pyrrolyle, ou-bien, R2 et R3, lorsqu'ils sont situés sur des carbones adjacents, forment avec les atomes de carbone qui les portent, un noyau furane ou phényle, leurs isomères ainsi que leurs sels d'addition à un acide pharmaceutiquement acceptable.

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