New bispidine compounds useful in the treatment of cardiac...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/08 (2006.01) A61K 31/435 (2006.01) C07D 471/20 (2006.01)

Patent

CA 2377395

There is provided compounds of formula (I), wherein R1, R2, R3, R4, R5a, R5b, R5c, R5d, R5e, R5f, R6, X, A, B and D have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.

La présente invention concerne des composés de formule (I) dans R?1¿, R?2¿, R?3¿, R?4¿, R?5a¿, R?5b¿, R?5c¿, R?5d¿, R?5e¿, R?5f¿, R?6¿, X, A, B et D correspondent aux éléments donnés dans la description. Ces composés peuvent être utilisés pour la prévention et le traitement de l'arythmie, en particulier de l'arythmie auriculaire et ventriculaire.

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