New chiral intermediate, process for producing the same and...

C - Chemistry – Metallurgy – 07 – D

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C07D 311/20 (2006.01) A61K 31/353 (2006.01)

Patent

CA 2647990

The compound of formula (I): is provided. It may be produced by subjecting a compound of formula (IV) to a reduction reaction wherein R represents hydrogen, straight or branched C1-C6 alkyl. This compound is a valuable intermediate which may be used in the synthesis of fesoterodine, tolterodine, its active metabolite, and related compounds.

L'invention propose un composé représenté par la formule (I), lequel est obtenu en soumettant un composé de formule (IV) à une réaction de réduction dans laquelle R représente hydrogène, alkyle en C1-C6 à chaîne droite ou ramifié. Ce composé est un intermédiaire de valeur qui peut être utilisé dans la synthèse de la fésotérodine, de la toltérodine, de son métabolite actif et de composés apparentés.

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