New cholest-4-en-3-one oxime derivatives, pharmaceutical...

C - Chemistry – Metallurgy – 07 – J

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C07J 41/00 (2006.01) A61K 31/575 (2006.01) A61P 25/28 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2633633

Compound of the formula (I) in which X represents an oxygen atom or an =N-OH group and R represents a group selected from (II) or one of its esters and/or its addition salts with pharmaceutically acceptable acids, particularly as a cytoprotective, preferably cardioprotective and/or neuroprotective, medicament; the compounds of formula I in which R is R2, R3, R4, R5 or R6, as new compounds; and also their preparation process, and the use.

L'invention a pour objet l'utilisation à titre de médicament d'un composé répondant a Ia formule (I) ou de I'un de ses esters et/ou de ses sels d'addition avec les acides pharmaceutiquement acceptables, particulièrement comme médicament cytoprotecteur, préfèrentiellement cardioprotecteur et/ou neuroprotecteur.

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