New co-crystal compound of rivaroxaban and malonic acid

Details New co-crystal compound of rivaroxaban and malonic acid New co-crystal compound of rivaroxaban and malonic acid

C - Chemistry, Metallurgy

07

D

C07D 413/14 (2006.01) A61K 31/5377 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2727378

The present invention relates to a new co-crystal compound of 5-chloro-N- ({(5S)-2-oxo-3-[4-(3-oxo-4-morpholi- nyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophenecarboxamide (rivaroxaban) and malonic acid, to processes for preparing it, to medicinal products comprising it, and to the use thereof in fighting diseases.

La présente invention concerne un nouveau composé de 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phényl]-1,3-oxazolidin-5-yl}-méthyl)-2-thiophènecarboxamide (rivaroxaban) et d'acide malonique contenant des co-cristaux, son procédé de préparation, les médicaments contenant ce nouveau composé ainsi que leur utilisation pour lutter contre des maladies.

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