New combination of anti-madcam antibody and antifibrotic...

Details New combination of anti-madcam antibody and antifibrotic... New combination of anti-madcam antibody and antifibrotic...

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 31/198 (2006.01) A61P 1/16 (2006.01)

Patent

CA 2614622

The invention relates to a new combination of an anti-MAdCAM antibody with an anti-fibrotic agent, such as a protease inhibitor, preferably a caspase inhibitor. The invention also relates to pharmaceutical compositions comprising the combination of the invention, and the use of the combination for the treatment of liver fibrosis.

L'invention concerne une nouvelle combinaison d'un anticorps anti-MAdCAM et d'un agent anti-fibrotique, tel qu'un inhibiteur de protéase, de préférence un inhibiteur de caspase. L'invention concerne également des compositions pharmaceutiques comprenant la combinaison susmentionnée ainsi que l'utilisation de cette combinaison pour le traitement de la fibrose du foie.

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