C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 229/64 (2006.01) A61K 31/195 (2006.01) A61K 31/275 (2006.01) C07C 205/59 (2006.01) C07C 255/59 (2006.01) C07C 323/62 (2006.01) C07C 323/63 (2006.01) C07F 7/10 (2006.01)
Patent
CA 2115161
2115161 9305012 PCTABS00020 The present invention relates to novel derivatives of 3-hydroxyanthranilic acid of general formula (I), methods for their preparation, novel pharmaceutical compositions and the use thereof for inhibiting the enzyme 3-hydroxyanthranilate oxygenase, 3-HAO, responsible for the production of the endogenous neurotoxin quinolinic acid, QUIN.
Bjork Susanna Karin Maria
Carpenter Barry
Gotthammar Kristina Birgitta
Hagberg Curt-Eric
Hogberg Thomas
Aktiebolaget Astra
Fetherstonhaugh & Co.
University Of Maryland At Baltimore
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