C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 309/66 (2006.01) A61K 31/255 (2006.01) C07C 309/73 (2006.01) C07C 311/48 (2006.01)
Patent
CA 2469227
The present invention relates to novel antidiabetic, hypolipidemic, antiobesity and hypocholesterolemic compounds of formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. More particularly, the present invention relates to compounds of the general formula (I) which are predominantly PPAR alpha agonists, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them The present invention also relates to processes for the preparation of novel compounds of formula (I), novel intermediates, processes for their preparation, use of the novel intermediates in the preparation of the above said compounds and their use as antidiabetic, hypolipidemic, antiobesity and hypocholesterolemic compounds.
L'invention concerne de nouveaux composés antidiabétiques, hypolipémiants, anti-obésité et hypocholestérolémiques de formule (I), leurs dérivés, leurs analogues, leurs formes tautomères, leurs stéréoisomères, leurs polymorphes, leurs sels pharmaceutiquement acceptables, leurs solvates pharmaceutiquement acceptables et les compositions pharmaceutiquement acceptables les contenant. Plus précisément, l'invention concerne des composés de la formule générale (I) qui sont principalement des agonistes de PPAR .alpha., leurs dérivés, leurs analogues, leurs formes tautomères, leurs sétéréoisomères, leurs polymorphes, leurs sels pharmaceutiquement acceptables, leurs solvates pharmaceutiquement acceptables et les compositions pharmaceutiquement acceptables les contenant. L'invention concerne également des procédés de préparations de nouveaux composés de formule (I), de nouveaux intermédiaires, leurs procédés de préparation, l'utilisation des nouveaux intermédiaires dans la préparation desdits composés et leur utilisation comme composés antidiabétiques, hypolipémiants, anti-obésité et hypocholestérolémiques.
Bhuniya Debnath
Chakrabarti Ranjan
Das Saibal Kumar
Iqbal Javed
Madhavan Gurram Ranga
Dr. Reddy's Laboratories Ltd.
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