C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/4355 (2006.01) A61K 31/444 (2006.01) A61K 31/4995 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2737527
The present invention relates to compounds of formula (I) and their pharmaceutically acceptable salts, solvates, hydrates, geometrical isomers, tautomers, optical isomers or N-oxides, which are inhibitors of SSAO activity. The invention further relates to pharmaceutical compositions comprising these compounds and to the use of these compounds for the treatment of medical conditions wherein inhibition of SSAO activity is beneficial, such as inflammatory diseases and immune disorders.
La présente invention concerne des composés de formule (I) et leurs solvates, hydrates, isomères géométriques, tautomères, isomères optiques, N-oxydes ou sels pharmaceutiquement acceptables, qui sont des inhibiteurs de l'activité SSAO. L'invention concerne, en outre, des compositions pharmaceutiques comprenant ces composés et l'utilisation de ces composés en vue du traitement d'affections médicales pour lesquelles l'inhibition de l'activité SSAO se révèle bénéfique, comme, par exemple, dans le cas des maladies inflammatoires et des troubles immunitaires.
Higginbottom Michael
Horgan Anne Viet-Anh
Oliver Kathryn
Savory Edward
Gowling Lafleur Henderson Llp
Proximagen Limited
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