New compounds of the secomacrolide and secoazalide class and...

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 15/26 (2006.01) C07H 15/04 (2006.01)

Patent

CA 2164152

The present invention provides new compounds of the secomacrolide and secoazalide class of general formula (I), a process for the preparation thereof as well as to new intermediates for the preparation of these seco derivatives. Image wherein R1 and R2 are the same and represent H or CH3, r3 and R4 are different and represent H or CH3, Y is O or NH, and Z is CH3 or the CH(CH3)CH(OH)COH(CH3)CH(OH)C2H5 group, or their pharmaceutically acceptable addition salts with inorganic or organic acids.

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