New conditions for reactions mediated by yeast

Details New conditions for reactions mediated by yeast New conditions for reactions mediated by yeast

C - Chemistry, Metallurgy

12

P

C12P 1/02 (2006.01) C07C 213/02 (2006.01) C12P 7/24 (2006.01) C12P 7/26 (2006.01) C12P 7/40 (2006.01) C12P 13/00 (2006.01) C12P 13/02 (2006.01) C12P 17/02 (2006.01) C07C 217/48 (2006.01)

Patent

CA 2462063

Organic compounds, such as precursors for aryl ethylamines such as ephedrine, aryl propylamines such as fluoxetine and propionic acid derivatives such as ibuprofen, naproxen and fenoprofen, are subjected to a yeast mediated reduction conducted in the absence of a solvent. The yeast is moistened with water and contacted with the organic compound. The yeast may then be contacted with an organic solvent to dissolve the product of the reaction into the solvent, and a solid/liquid separation used to separate the product from the yeast.

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