New controlled release active agent carrier

Details New controlled release active agent carrier New controlled release active agent carrier

A - Human Necessities

61

K

A61K 9/14 (2006.01) A61K 47/12 (2006.01)

Patent

CA 2737395

The present invention relates to carriers for the controlled release of active agents, comprising surface reacted natural or synthetic calcium carbonate, one or more active agents, wherein said one or more active agent is associated with said surface- reacted calcium carbonate, and wherein said surface-reacted natural or synthetic calcium carbonate is a reaction product of natural or synthetic calcium carbonate with carbon dioxide and one or more acids, wherein the carbon dioxide is formed in situ by the acid treatment and/or is supplied from an external source. It further relates to the preparation of loaded carriers, as well as their use in different applications.

La présente invention porte sur des vecteurs pour la libération contrôlée d'agents actifs, comprenant du carbonate de calcium naturel ou synthétique ayant réagi en surface, un ou plusieurs agents actifs, ledit ou lesdits agents actifs étant associés audit carbonate de calcium ayant réagi en surface et ledit carbonate de calcium naturel ou synthétique ayant réagi en surface étant un produit de réaction de carbonate de calcium naturel ou synthétique avec du dioxyde de carbone et un ou plusieurs acides, le dioxyde de carbone étant formé in situ par le traitement acide et/ou étant introduit à partir d'une source externe. L'invention porte en outre sur la préparation de vecteurs chargés, ainsi que sur leur utilisation dans différentes applications.

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