New crystalline form of a vitamin d analogue

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 401/00 (2006.01) A61K 31/59 (2006.01)

Patent

CA 2151730

A novel form of calcipotriol, namely calcipotriol (1.alpha., 3.beta., 5Z 7E 22E 24S)-24- cyclopropyl-9,10-secochola-5,7,10(19), 22-tetraene-1,3,24-triol, monohydrate is provided herein. This calcipotriol is characterized by its storage stability at 40°C after 12 months, its ready wettability and wet ball milling characteristics. This product is perfectly crystalline, stable and well suited for its use in modern therapy.

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